verb \ pruh-tay-go\    Latin “to protect”
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Praetego is a pharmaceutical company committed to improving health outcomes in neurodegenerative diseases associated with aging, starting with Alzheimer’s disease.

Praetego’s novel small molecules, the Amadorins, have a unique mechanism of action with the potential to provide systemic protection against neurodegeneration associated with glycoxidation. These features are reflected in our animal data and provide promising indications of clinical benefit.


Praetego was founded on rigorous and extensive science and the desire to offer a potent oral drug for neurodegenerative diseases associated with aging. Our proprietary small molecule technology inhibits an established driver of disease pathology in neurodegeneration, diabetic microvascular disease, and aging.

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At Praetego, we are committed to addressing neurodegenerative diseases associated with aging. Praetego’s management team led the discovery and development of the Amadorins. Our clinicians are leaders in the field of neurology and neurodegeneration. Complimented by guidance from industry veterans, the Praetego team has extensive technical and operational experience in developmental stage drug companies.

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Praetego’s Amadorins have demonstrated preclinical proof of efficacy in Alzheimer’s disease and Diabetic Peripheral Neuropathy. We have two candidates under development, lead PTG-630 and PTG-670. Our Alzheimer's Disease program leads the pipeline and is complemented by our efforts in Diabetic Peripheral Neuropathy and Diabetic Retinopathy.

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Press and Announcements

Praetego awarded $2.5M from NIA to continue Alzheimer’s work

October 4, 2022

Praetego Inc, a pharmaceutical company committed to protecting patients from neurodegenerative diseases related to aging, is pleased to announce a $2.5M STTR award from the National Institute of Aging (NIA). The Phase 2 award advances Praetego’s lead candidate, PTG-630, against Alzheimer’s disease (AD).

Praetego Wins RESI Longevity Innovator’s Pitch Challenge

September 30, 2021

Praetego wins Innovator’s Pitch Challenge at RESI Longevity